1-(4-Chlorophenyl)-2-butyn-1-ol → (Z)-1-(4-chlorophenyl)-2-buten-1-ol

HRID 1380346

반응식

HRID 1380346 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:12])[C:9]#[C:10][CH3:11])=[CH:4][CH:3]=1>[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([OH:12])/[CH:9]=[CH:10]\[CH3:11])=[CH:6][CH:7]=1

참가 물질

3

반응물 1

HCID 201883391-(4-Chlorophenyl)-2-butyn-1-ol

생성물 1

HCID 67901371(Z)-1-(4-chlorophenyl)-2-buten-1-ol

시약·촉매·용매 1

HCID 131709914Lindlars catalyst촉매

실험 절차

Under nitrogen, hydrogenate a mixture of 10 g (0.055 mole) of 1-(4-chlorophenyl)-2-butyn-1-ol and 0.6 g Lindlar catalyst. Following the reaction via NMR the reaction is complete in about two days. The hydrogenation is stopped and the reaction stirred under N2 at room temperature overnight. Filter off the catalysts, wash with methylene chloride combine the filtrate and evaporate to yield the title compound.

후처리

  1. customthe reaction via NMR the reaction
  2. filtrationFilter off the catalysts
  3. washwash with methylene chloride
  4. customevaporate

출처 및 근거

ORD 기록
ord-413af3631eaf47fdb58ab7913b111ccb
출처 데이터셋
uspto-grants-1986_04
특허 번호
US04581370

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