참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,3-Diaminopyridine | HCID 9956 | — |
| 반응물 | 4-Amino-o-anisic acid | HCID 75599 | — |
| 반응물 | 4-(Chlorosulfonyl)-2-methoxybenzoic acid | HCID 20184580 | — |
| 용매 | Phosphorus oxychloride | HCID 24813 | — |
| 생성물 | HCID 178493630 | HCID 178493630 | — |
반응 단계
Five grams of 2-methoxy-4-chlorosulfonyl-benzoic acid (prepared from 4-amino-2-methoxy-benzoic acid via the corresponding diazonium compound) were dissolved in 400 ml of phosphorus oxychloride and heated to 80° C. for 30 minutes. Then, 3.6 gm of 2,3-diaminopyridine were added, and the mixture was refluxed for four hours. The reaction mixture was concentrated by evaporation in vacuo and re-evaporated with toluene, and the solid residue was processed further without any other purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04582837 |
|---|
| 출처 데이터셋 | uspto-grants-1986_04 |
|---|
| ORD ID | ord-94633bad767d4d8fbfd17521349fbbb8 |
|---|
| 출처 메모 | uspto-grants-1986_04 |
|---|
