Methanesulfonyl chloride → 2-(2'-Methoxy-3'-methanesulfonyloxy-phenyl)-imidazo[4,5-b]pyridine

반응식

[CH3:1][O:2][C:3]1[C:8]([OH:9])=[CH:7][CH:6]=[CH:5][C:4]=1[C:10]1[NH:11][C:12]2[C:13]([N:18]=1)=[N:14][CH:15]=[CH:16][CH:17]=2.[CH3:19][S:20](Cl)(=[O:22])=[O:21]>>[CH3:1][O:2][C:3]1[C:8]([O:9][S:20]([CH3:19])(=[O:22])=[O:21])=[CH:7][CH:6]=[CH:5][C:4]=1[C:10]1[NH:11][C:12]2[C:13]([N:18]=1)=[N:14][CH:15]=[CH:16][CH:17]=2

참가 물질

반응물 2

HCID 31297Methanesulfonyl chloride

HCID 201845143-(1H-Imidazo[4,5-b]pyridin-2-yl)-2-methoxyphenol

생성물 1

HCID 132820562-(2'-Methoxy-3'-methanesulfonyloxy-phenyl)-imidazo[4,5-b]pyridine

실험 절차

Prepared analogously to Example 1 from 2-(2'-methoxy-3'-hydroxy-phenyl)-imidazo[4,5-b]pyridine and methanesulfonic acid chloride.

출처 및 근거

ORD 기록: ord-8b5b3982275e4040a993d97670d6a033
출처 데이터셋: uspto-grants-1986_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04582837

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