4,5-Diaminopyrimidine → N-[3-Methoxy-4-(7H-purin-8-yl)phenyl]methanesulfonamide

반응식

[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][N:5]=[CH:4][N:3]=1.[CH3:9][O:10][C:11]1[CH:19]=[C:18]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[CH:17]=[CH:16][C:12]=1[C:13](O)=O>>[CH3:9][O:10][C:11]1[CH:19]=[C:18]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[CH:17]=[CH:16][C:12]=1[C:13]1[NH:8][C:7]2[C:2](=[N:3][CH:4]=[N:5][CH:6]=2)[N:1]=1

참가 물질

반응물 2

HCID 837034,5-Diaminopyrimidine

HCID 121193062-Methoxy-4-[(methylsulfonyl)amino]benzoic acid

생성물 1

HCID 13284519N-[3-Methoxy-4-(7H-purin-8-yl)phenyl]methanesulfonamide

실험 절차

Prepared analogously to Example 14 from 4,5-diaminopyrimidine and 2-methoxy-4-methanesulfonylamino-benzoic acid.

출처 및 근거

ORD 기록: ord-ac371a45fb40466bb917e02215e90103
출처 데이터셋: uspto-grants-1986_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04582837

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