Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Nitro-3-phenylheptanedioic acid dimethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Methyl Acrylate | HCID 7294 | — |
| 반응물 | Benzenepropanoic acid, b-(nitromethyl)-, methyl ester | HCID 10537045 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | tert-Butanol | HCID 6386 | — |
| 생성물 | 4-Nitro-3-phenylheptanedioic acid dimethyl ester | HCID 13649246 | — |
반응 단계
A solution of 356 g of 4-nitro-3-phenylbutanoic acid methyl ester, 138 g of methyl acrylate, and 25 ml of Triton B in 500 ml of t-butanol is allowed to stir at room temperature for 94 hours. Excess aqueous hydrochloric acid (1 N) is added and the solution is diluted with diethyl ether. The organic layer is separated, dried over anhydrous magnesium sulfate and evaporated to give 4-nitro-3-phenylheptanedioic acid dimethyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04584313 |
| 출처 데이터셋 | uspto-grants-1986_04 |
| ORD ID | ord-3f4c7e6ec30141ae967858d614e0af35 |
| 출처 메모 | uspto-grants-1986_04 |