Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosgene → N-chloroformyl-3-(m-chloroanilino)propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosgene | HCID 6371 | — |
| 반응물 | 7-Chloro-2,3-dihydro-4-quinolone | HCID 88974 | — |
| 반응물 | 3-((3-Chlorophenyl)amino)propanoic acid | HCID 12470919 | — |
| 생성물 | N-chloroformyl-3-(m-chloroanilino)propionic acid | HCID 13457253 | — |
반응 단계
A process of the preparation of 7-chloro-1,2,3,4-tetrahydro-4-quinolinone which comprises treating 3-(m-chloro-anilino)propionic acid with phosgene to produce N-chloroformyl-3-(m-chloroanilino)propionic acid, converting the said product, by the action of an organic base or by heating, into 3-(m-chlorophenyl)-2,6-dioxo-1,3-perhydrooxazine, and treating the latter with aluminium chloride in an inert organic solvent or with a strong acid, to provide 7-chloro-1,2,3,4-tetrahydro-4-quinolinone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04585867 |
| 출처 데이터셋 | uspto-grants-1986_04 |
| ORD ID | ord-747c8bb1ce0746fdad3b5d4d2ff2a4d4 |
| 출처 메모 | uspto-grants-1986_04 |