1-(Triphenylphosphoranylidene)acetone → HCID 23035652, 화합물

HRID 1381631노트

반응식

HRID 1381631 반응식
[C:1]([CH:4]=P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)(=[O:3])[CH3:2].[C:24]1([N:30]2[CH:33]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)[C:32](=O)[C:31]2=[O:41])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>C1C=CC=CC=1>[O:3]=[C:1]([CH3:4])/[CH:2]=[C:32]1/[C:31](=[O:41])[N:30]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:33]/1[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

참가 물질

4

반응물 2

HCID 150381-(Triphenylphosphoranylidene)acetoneHCID 133600861,4-Diphenylazetidine-2,3-dione

생성물 1

HCID 23035652HCID 23035652, 화합물

시약·촉매·용매 1

HCID 241Benzene용매2회

실험 절차

To a solution of 0.67 g of acetylmethylene triphenylphosphorane in 70 ml of benzene was added at room temperature under a nitrogen atmosphere a solution of 0.50 g of 1,4-diphenyl-2,3-azetidinedione in 30 ml of benzene, and the mixture was stirred overnight. After completion of the reaction, the benzene was evaporated, and the residue was applied to silica gel column chromatography (eluent; methylene chloride). The desired fractions were combined, the solvent was evaporated, and the residue was recrystallized from ethanol to give the title compound as pale yellow needles. Yield 0.32 g, m.p. 157.5°-158.5° C.

후처리

  1. customAfter completion of the reaction
  2. customthe benzene was evaporated
  3. customthe solvent was evaporated
  4. customthe residue was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-49b56e971ba74661bab039432acaa0e9
출처 데이터셋
uspto-grants-1989_02
특허 번호
US04803266

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