(+-)(2R,3S)-2-Methyl-2-nitro-1,3-butanediol → (+-)(2R,3S)-2-amino-2-methyl-1,3-butanediol acetate

반응식

[C:1]([OH:4])(=[O:3])[CH3:2].[NH2:5][C@@:6]([CH3:12])([C@H:9]([OH:11])[CH3:10])[CH2:7][OH:8].C[C@]([N+]([O-])=O)([C@@H](O)C)CO>>[C:1]([OH:4])(=[O:3])[CH3:2].[NH2:5][C@@:6]([CH3:12])([C@@H:9]([OH:11])[CH3:10])[CH2:7][OH:8]

참가 물질

반응물 2

HCID 13375424(+-)(2R*,3S*)-2-Methyl-2-nitro-1,3-butanediol

HCID 86741969(+-)(2R*,3R*)-2-amino-2-methyl-1,3-butanediol acetate

생성물 1

HCID 86741966(+-)(2R*,3S*)-2-amino-2-methyl-1,3-butanediol acetate수율 93%

실험 절차

Using the procedure described for 5E (+-)(2R*,3S*)-2-methyl-2-nitro-1,3-butanediol (5A) gave (+-)(2R*,3S*)-2-amino-2-methyl-1,3-butanediol acetate (93%) mp 163°-165° (C, H, N).

출처 및 근거

ORD 기록: ord-d6db93f1f06141009af80d15afe6a662
출처 데이터셋: uspto-grants-1989_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04803222

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