2-Bromopropanoyl chloride → HCID 15611036, 화합물

HRID 1382159

반응식

HRID 1382159 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[CH:5][C:4]=1[S:11]([NH2:14])(=[O:13])=[O:12].[Br:15][CH:16]([CH3:20])[C:17](Cl)=[O:18]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[CH:5][C:4]=1[S:11]([NH:14][C:17](=[O:18])[CH:16]([Br:15])[CH3:20])(=[O:13])=[O:12]

참가 물질

3

반응물 2

HCID 979802-Bromopropanoyl chlorideHCID 209044Benzenesulfonamide, 2,5-dimethoxy-

생성물 1

HCID 15611036HCID 15611036, 화합물

실험 절차

A stirred mixture of 7.0 g (0.032 mole) of 2,5-dimethoxyphenylsulfonamide in 10 mL of 2-bromopropionyl chloride was heated at reflux for 40 minutes then allowed to cool to room temperature. The resultant solution was poured into petroleum ether. Crystals formed after scratching the sides of the flask and were collected by filtration. The filter cake was washed four times with fresh petroleum ether to yield 10.3 g of N-(2,5-dimethoxyphenylsulfonyl)-2-bromopropionamide (mp 116°-118° C.).

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 40 minutes
  3. customCrystals formed
  4. filtrationwere collected by filtration
  5. washThe filter cake was washed four times with fresh petroleum ether

출처 및 근거

ORD 기록
ord-5a22b3ebdf9b41f48650b929e3982123
출처 데이터셋
uspto-grants-1989_02
특허 번호
US04806145

연결된 노트

불러오는 중…