Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2,2-Trifluoroacetophenone → 2-Phenyl-3,3,3-trifluoro-1-(4-fluorophenyl)-propene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2,2-Trifluoroacetophenone | HCID 9905 | — |
| 반응물 | Sodium ethoxide | HCID 2723922 | — |
| 반응물 | (4-Fluorobenzyl)triphenylphosphonium chloride | HCID 2733554 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Phenyl-3,3,3-trifluoro-1-(4-fluorophenyl)-propene | HCID 57056367 | 90% |
반응 단계
2,2,2-Trifluoroacetophenone is reacted with triphenyl-(4-fluorobenzyl)-phosphonium chloride (R. A. Jones: Australian J. Chem. 18, 903-6 (1965) in ethanol in the presence of sodium ethoxide. 2-Phenyl-3,3,3-trifluoro-1-(4-fluorophenyl)-propene is obtained with a yield of 90%; b.p.: 105°-107° C./0.2 mm Hg, m.p.: 35°-41° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04806685 |
| 출처 데이터셋 | uspto-grants-1989_02 |
| ORD ID | ord-018a985c58db4b17bdd4b5052bf80006 |
| 출처 메모 | uspto-grants-1989_02 |