참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,1-Dibutoxytrimethylamine | HCID 87683 | — |
| 반응물 | 5-Acetyl-6-amino-1,3-dimethyluracil | HCID 320023 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 178481358 | HCID 178481358 | 70.2% |
반응 단계
0.8 g of 5-acetyl-6-amino-1,3-dimethyluracil was dissolved in DMF and 4 ml of dimethylformamide dibutylacetal was added thereto. The solution was heated for 8 hr at 80° C. and distilled under reduced pressure. After purification by silica gel column chromatography, the crude product was recrystallized from ethanol to give 0.59 g of 5-hydroxy1,3-dimethylpyrido[2,3-d]pyrimidine-2,4-dione (Compound 14).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04808587 |
|---|
| 출처 데이터셋 | uspto-grants-1989_02 |
|---|
| ORD ID | ord-303b74edd28c4f0da0843227cddd9aa1 |
|---|
| 출처 메모 | uspto-grants-1989_02 |
|---|
