1-Bromo-4-(trifluoromethoxy)benzene → 2-(4'-Trifluoromethoxybiphenyl-4-yl)-5-propylpyrimidine

반응식

[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([CH2:14][CH2:15][CH3:16])[cH:12][n:13]2)[cH:6][cH:7]1.[F:17][C:18]([O:19][c:20]1[cH:21][cH:22][c:23]([Br:26])[cH:24][cH:25]1)([F:27])[F:28]>>[c:2]1(-[c:23]2[cH:22][cH:21][c:20]([O:19][C:18]([F:17])([F:27])[F:28])[cH:25][cH:24]2)[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([CH2:14][CH2:15][CH3:16])[cH:12][n:13]2)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 5210081-Bromo-4-(trifluoromethoxy)benzene

HCID 136514502-(4-Bromophenyl)-5-propylpyrimidine

생성물 1

HCID 144384522-(4'-Trifluoromethoxybiphenyl-4-yl)-5-propylpyrimidine

출처 및 근거

ORD 기록: ord-0cb2cf6471474ccea26c1611ff370cf1
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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