tert-Butyl carbazate → t-Butyl 3-(1-methyl-3-phenylpropen-2-yl)carbazate

HRID 1384086

반응식

HRID 1384086 반응식
[C:1]1(/[CH:7]=[CH:8]/[C:9](=O)[CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:12]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])(=[O:15])[NH:13][NH2:14]>>[CH3:10][CH:9]=[C:8]([NH:14][NH:13][C:12]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 70091tert-Butyl carbazateHCID 637759Benzylideneacetone

생성물 1

HCID 69852452t-Butyl 3-(1-methyl-3-phenylpropen-2-yl)carbazate

실험 절차

This compound was prepared by the method of Ghali et al. (J. Org. Chem., 1981, 46, 5413-5414) in about 65% overall yield, from trans-4-phenyl-3-buten-2-one and t-butyl carbazate, after crystallization of the crude product from hexane; melting point=76-79° C.; NMR (CDCl3) 1.24 (d, 3H, CH3); 1.45 (s, 9H, t-butyl CH3); 3.78 (m, 2H, propenyl CH-1, carbazate NH-3); 5.8-6.29 (m, 2H, carbazate NH-2, propenyl CH-2); 6.53 (d, 1H, propenyl CH-3); 7.3 (m, 5H, aromatic).

후처리

  1. customafter crystallization of the crude product from hexane

출처 및 근거

ORD 기록
ord-99c0bfe7342f4e53bef7575a4ef22087
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06258806B1

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