Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-6,7-dimethoxy-4-quinazolinamine → 6,7-Dimethoxyquinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-6,7-dimethoxy-4-quinazolinamine | HCID 90235 | — |
| 반응물 | 1-(Cyclohexylcarbonyl)piperazine | HCID 3437502 | — |
| 생성물 | 6,7-Dimethoxyquinazoline | HCID 3031661 | — |
반응 단계
N-(Cyclohexylcarbonyl)piperazine (5.9 g., 0.03 mole) and 2-chloro-4-amino-6,7-dimethoxyquinazoline (7.2 g., 0.03 mole) are reacted according to the procedure of Example 127(a). The crude product crystallized from methanol affords analytically pure 4-amino-2-4-(cyclohexylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazoline, m.p. 223°-225° C., resolidifying and remelting at 248.0°-250.0° C. (corr.)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06262059B1 |
| 출처 데이터셋 | uspto-grants-2001_07 |
| ORD ID | ord-f76035956259415ca00a0a7107bbf1b2 |
| 출처 메모 | uspto-grants-2001_07 |