Bromocyclobutane → HCID 53784624, 화합물

반응식

[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][NH:11]2)=[CH:7][CH:6]=1)=[O:4].[CH:16]1(Br)[CH2:19][CH2:18][CH2:17]1>>[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][N:11]2[CH:16]2[CH2:19][CH2:18][CH2:17]2)=[CH:7][CH:6]=1)=[O:4]

참가 물질

반응물 2

HCID 78110Bromocyclobutane

HCID 178438014HCID 178438014, 화합물

생성물 1

HCID 53784624HCID 53784624, 화합물수율 32.4%

실험 절차

This compound was prepared according to the method of Preparation 3, using 750 mg (3.67 mmol, 1.0 equiv) 3-ethyl-1H-indazole-6-carboxylic acid methyl ester and 0.38 mL (4.04 mmol, 1.1 equiv) cyclobutyl bromide as starting materials to give 307 mg (32%) of a clear oil: HRMS calcd for C15H18N2O2+H: 259.1447. Found: 259.14550.

후처리

customThis compound was prepared
customaccording to the method of Preparation 3

출처 및 근거

ORD 기록: ord-dce07301f5604737a3977754792974bb
출처 데이터셋: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06262040B1

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