Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 2-(4-bromo-2-nitrophenyl)acetate → 6-bromo-2,3-dihydro-1H-indol-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 2-(4-bromo-2-nitrophenyl)acetate | HCID 23247724 | — |
| 촉매 | Iron | HCID 23925 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 6-bromo-2,3-dihydro-1H-indol-2-one | HCID 2773289 | 43% |
반응 단계
Using a procedure analogous to that described for the starting material in Example 57, ethyl(4-bromo-2-nitrophenyl)acetate (26 g, 90 mmol) was treated with iron in acetic acid. The product thus obtained was recystallised from ether/isohexanes to give 6-bromooxindole (8.2 g, 42%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06265411B1 |
| 출처 데이터셋 | uspto-grants-2001_07 |
| ORD ID | ord-f7fae3e4e5694ee78bf254612174d1f3 |
| 출처 메모 | uspto-grants-2001_07 |