Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Iodide → 8-Iodo-1-octyne
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | Oct-7-yn-1-yl 4-methylbenzene-1-sulfonate | HCID 10779145 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 8-Iodo-1-octyne | HCID 22621556 | 94.2% |
반응 단계
A mixture of 7-octynyl-p-toluenesulfonate (18.3 g, 65.2 mmol), sodium iodide (9.77 g, 65.2 mmol) and acetone (91 ml) was allowed to react for four hours under reflux. After cooling, the precipitates were removed by filtration, and the filtrate was concentrated. The resulting residue was purified by silica gel column chromatography (eluent; hexane) to afford 14.5 g of 8-iodo-1-octyne (yield; 94.2%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06265569B1 |
| 출처 데이터셋 | uspto-grants-2001_07 |
| ORD ID | ord-31fa64294bc44b35b52744d807888dcc |
| 출처 메모 | uspto-grants-2001_07 |