HCID 11833645, 화합물 → 2-methyl-2-(naphthalen-2-yl)propanoic acid

HRID 1387296노트

반응식

HRID 1387296 반응식
C([O:8][C:9](=[O:23])[C:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)([CH3:12])[CH3:11])C1C=CC=CC=1>C(O)C.[Pd]>[CH3:12][C:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)([CH3:11])[C:9]([OH:23])=[O:8]

참가 물질

4

반응물 1

HCID 11833645HCID 11833645, 화합물

생성물 1

HCID 117905652-methyl-2-(naphthalen-2-yl)propanoic acid수율 100%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A mixture of 2,2-dimethyl-(2-naphthyl)acetic acid benzyl ester (0.46 g, 1.5 mmol) and 10% Pd/C (0.040 g) in ethanol (5 mL) was hydrogenated at 1 atmosphere for 16 hours. The catalyst was removed by filtration, and the solvent was evaporated to give 2,2-dimethyl-(2-naphthyl)acetic acid (0.33 g, 1.5 mmol, 100%).

후처리

  1. customThe catalyst was removed by filtration
  2. customthe solvent was evaporated

출처 및 근거

ORD 기록
ord-c24e74c9437f49e7af5c9edc6e972b1c
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06268365B1

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