3-Amino-4-methoxybenzanilide → 3-[3-(3-Nitrophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide

HRID 1387537

반응식

HRID 1387537 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:6].[N+:19]([C:22]1[CH:23]=[C:24]([N:28]=[C:29]=[S:30])[CH:25]=[CH:26][CH:27]=1)([O-:21])=[O:20]>>[N+:19]([C:22]1[CH:23]=[C:24]([NH:28][C:29](=[S:30])[NH:1][C:2]2[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:5]([NH:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:6])[CH:25]=[CH:26][CH:27]=1)([O-:21])=[O:20]

참가 물질

3

반응물 2

HCID 84263-Amino-4-methoxybenzanilideHCID 19050Benzene, 1-isothiocyanato-3-nitro-

생성물 1

HCID 104773203-[3-(3-Nitrophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide수율 87.6%

실험 절차

Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.243 g, 1.0 mmol) and 3-nitrophenyl isothiocyanate (0.183 g, 1.0 mmol). Trituration in hexanes/ethyl acetate (4:1) gave the product (0.370 g); m.p. 188-189° C.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-9cf7668fae0543758425849fd9fde2df
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06268387B1

연결된 노트

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