3-Amino-4-methoxybenzanilide → 3-(Quinoline-8-sulfonylamino)-4-methoxy-N-phenyl-benzamide

HRID 1387577노트

반응식

HRID 1387577 반응식
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[S:11](Cl)(=[O:13])=[O:12])[CH:4]=[CH:3][CH:2]=1.[NH2:15][C:16]1[CH:17]=[C:18]([CH:28]=[CH:29][C:30]=1[O:31][CH3:32])[C:19]([NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[O:20]>>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[S:11]([NH:15][C:16]2[CH:17]=[C:18]([CH:28]=[CH:29][C:30]=2[O:31][CH3:32])[C:19]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:20])(=[O:13])=[O:12])[CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 84263-Amino-4-methoxybenzanilideHCID 292208-Quinolinesulfonyl chloride

생성물 1

HCID 98241853-(Quinoline-8-sulfonylamino)-4-methoxy-N-phenyl-benzamide수율 76.9%

실험 절차

Prepared according to the procedure described for Example 126 using 8-quinolinesulfonyl chloride (0.68 g, 3.0 mmol) and 3-amino-4-methoxy-N-phenyl-benzamide (0.73 g, 3.0 mmol) to afford the product (1.0 g); m.p. 187-188° C. after trituration in diethyl ether and recrystallization from ethanol.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-a73399f0eabd4b2ba072a2f5ebac777b
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06268387B1

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