Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Methyl-4-[(4-nitrobenzyl)sulfonyl]benzene → 4-[[(4-Methylphenyl)sulfonyl]methyl]benzenamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Methyl-4-[(4-nitrobenzyl)sulfonyl]benzene | HCID 800082 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 4-[[(4-Methylphenyl)sulfonyl]methyl]benzenamine | HCID 1508418 | 89.2% |
반응 단계
In ethanol (10 ml) and ethyl acetate (60 ml) was dissolved 4-methylphenyl 4-nitrobenzyl sulfone (0.5 g; G. Bram et al., Synthesis, 1987, 56-59). To the mixture was added 10% palladium on carbon (0.05 g) and catalytic hydrogenation was carried out at room temperature over night. The catalyst was filtered off, and the solvent was evaporated to give 4-aminobenzyl 4-methylphenyl sulfone (0.4 g) as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06268354B1 |
| 출처 데이터셋 | uspto-grants-2001_07 |
| ORD ID | ord-dd32a38fd8cb4e51ab2dbe13ae703829 |
| 출처 메모 | uspto-grants-2001_07 |