돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1387907생성일: 2026년 10월 26일

1-Methyl-4-[(4-nitrobenzyl)sulfonyl]benzene → 4-[[(4-Methylphenyl)sulfonyl]methyl]benzenamine

https://huagongshe.com/reaction/1387907

반응식

참여 물질

역할이름HCID투입량
반응물1-Methyl-4-[(4-nitrobenzyl)sulfonyl]benzeneHCID 800082—
촉매PalladiumHCID 23938—
용매EthanolHCID 702—
용매Ethyl AcetateHCID 8857—
생성물4-[[(4-Methylphenyl)sulfonyl]methyl]benzenamineHCID 150841889.2%

반응 단계

In ethanol (10 ml) and ethyl acetate (60 ml) was dissolved 4-methylphenyl 4-nitrobenzyl sulfone (0.5 g; G. Bram et al., Synthesis, 1987, 56-59). To the mixture was added 10% palladium on carbon (0.05 g) and catalytic hydrogenation was carried out at room temperature over night. The catalyst was filtered off, and the solvent was evaporated to give 4-aminobenzyl 4-methylphenyl sulfone (0.4 g) as colorless crystals.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06268354B1
출처 데이터셋uspto-grants-2001_07
ORD IDord-dd32a38fd8cb4e51ab2dbe13ae703829
출처 메모uspto-grants-2001_07