Ethanol → Diethyl toluene-2,4-dicarbamate

HRID 1388222

반응식

HRID 1388222 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([NH2:8])[CH:5]=[CH:4][C:3]=1[CH3:9].N[C:11](N)=[O:12].[C:14](=[O:19])([O:16][CH2:17][CH3:18])N.[CH2:20]([OH:22])[CH3:21]>>[CH2:17]([O:16][C:14]([NH:1][C:2]1[CH:7]=[C:6]([NH:8][C:11]([O:22][CH2:20][CH3:21])=[O:12])[CH:5]=[CH:4][C:3]=1[CH3:9])=[O:19])[CH3:18]

참가 물질

5

반응물 4

HCID 702EthanolHCID 1176UreaHCID 5641Carbamic acid, ethyl esterHCID 72612,4-Diaminotoluene

생성물 1

HCID 343975Diethyl toluene-2,4-dicarbamate

실험 절차

Following the procedure described in Example 1, 611 g of 2,4-diaminotoluene, 480 g of urea, 178 g of ethyl carbamate and 1590 g of ethanol (approximately 96%) were reacted for 6.5 hours at 200° C. in the pressure apparatus described in Example 1. After cooling and venting of the apparatus, the reaction mixture was removed, filtered and analyzed by liquid chromatography (HPLC). A yield of 881 g (66% of the theoretical yield) of 2,4-bis-(ethoxy carbonyl amino)-toluene was determined.

후처리

  1. customwere reacted for 6.5 hours at 200° C. in the pressure apparatus
  2. temperatureAfter cooling
  3. customthe reaction mixture was removed
  4. filtrationfiltered

출처 및 근거

ORD 기록
ord-3bf43103a77049c2bfe8cd027a42ed61
출처 데이터셋
uspto-grants-1984_02
특허 번호
US04430505

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