ethyl N,N'-diisopropylcarbamimidate → HCID 86739244, 화합물

HRID 1388272노트

반응식

HRID 1388272 반응식
[CH3:1][C:2]1([CH3:15])[C@H:4](/[CH:5]=[C:6]2/[C:7](=[O:11])[O:8][CH2:9][CH2:10]/2)[C@H:3]1[C:12]([OH:14])=[O:13].[CH:16](NC(=NC(C)C)OCC)(C)[CH3:17]>C(O)C>[CH3:1][C:2]1([CH3:15])[C@H:4](/[CH:5]=[C:6]2/[C:7](=[O:11])[O:8][CH2:9][CH2:10]/2)[C@H:3]1[C:12]([O:14][CH2:16][CH3:17])=[O:13]

참가 물질

4

반응물 2

HCID 20470583ethyl N,N'-diisopropylcarbamimidateHCID 70502571HCID 70502571, 화합물

생성물 1

HCID 86739244HCID 86739244, 화합물수율 56.6%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Using the procedure of Example 17, 7.8 g of (1R,trans) 2,2-dimethyl-3-[(E) (dihydro-2-oxo-3(2H)-furanylidene)-methyl]-cyclopropane-1-carboxylic acid and 7 g of ethyl N,N'-diisopropylcarbamimidate were reacted to obtain 5 g of ethyl (1R,trans) 2,2-dimethyl-3-[(E) (dihydro-2-oxo-3-(2H)-furanylidene)-methyl]-cyclopropane-1-carboxylate with a specific rotation of [α]D20 =+50°±2° (c=0.5% in ethanol).

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-de5b93e6fe2847c3ac69239ab79ce82d
출처 데이터셋
uspto-grants-1984_02
특허 번호
US04431576

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