Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → 4-(Trifluoromethoxy)benzoyl azide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | 18-Crown-6 | HCID 28557 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | Benzoyl fluoride, 4-(trifluoromethoxy)- | HCID 67612 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-(Trifluoromethoxy)benzoyl azide | HCID 13281314 | — |
반응 단계
A mixture of 5 grams (24 mmol) of 4-(trifluoromethoxy)benzoyl fluoride, 1.87 grams (29 mmol) of sodium azide, 0.2 grams of 18-Crown-6 ether, and 20 ml. of acetonitrile was stirred at room temperature for two hours under an atmosphere of dry nitrogen. The reaction mixture was diluted with diethyl ether, filtered and concentrated under reduced pressure, with a bath temperature of 40° C., to give the title compound as a turbid oil. IR showed adsorptions at 2280, 2240 and 1695 cm-1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04431667 |
| 출처 데이터셋 | uspto-grants-1984_02 |
| ORD ID | ord-f79fc335e7344fa0a0035b33648b6dbd |
| 출처 메모 | uspto-grants-1984_02 |