HCID 70633701, 화합물 → N-[N-[hexyl(phenylmethoxy)phosphinyl]-L-phenylalanyl]-L-leucine, phenylmethyl ester

HRID 1388690노트

반응식

HRID 1388690 반응식
[CH2:1]([PH:7](=[O:16])[O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].Cl.[NH2:18][C@H:19]([C:27]([NH:29][C@H:30]([C:35]([O:37][CH2:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)=[O:36])[CH2:31][CH:32]([CH3:34])[CH3:33])=[O:28])[CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:1]([P:7]([O:8][CH2:9][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)([NH:18][C@H:19]([C:27]([NH:29][C@H:30]([C:35]([O:37][CH2:38][C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1)=[O:36])[CH2:31][CH:32]([CH3:34])[CH3:33])=[O:28])[CH2:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[O:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

참가 물질

3

반응물 2

HCID 70633701HCID 70633701, 화합물HCID 178445555HCID 178445555, 화합물

생성물 1

HCID 131713394N-[N-[hexyl(phenylmethoxy)phosphinyl]-L-phenylalanyl]-L-leucine, phenylmethyl ester

실험 절차

Hexylphosphinic acid, phenylmethyl ester is reacted with L-phenylalanyl-L-leucine, phenylmethyl ester, hydrochloride salt according to the procedure of Example 1(c) to yield N-[N-[hexyl(phenylmethoxy)phosphinyl]-L-phenylalanyl]-L-leucine, phenylmethyl ester.

출처 및 근거

ORD 기록
ord-4eb7d16c0d67427088d8adebb65ee89e
출처 데이터셋
uspto-grants-1984_02
특허 번호
US04432972

반응 노트

불러오는 중…