Dodec-3-yn-1-ol → 3-Dodecen-1-ol, (3Z)-

HRID 1388879노트

반응식

HRID 1388879 반응식
[CH2:1]([OH:13])[CH2:2][C:3]#[C:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[H][H]>[Pd].CC([O-])=O.CC([O-])=O.[Pb+2].C(OCC)(=O)C>[CH2:1]([OH:13])[CH2:2]/[CH:3]=[CH:4]\[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

5

반응물 2

HCID 4108965Dodec-3-yn-1-olHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 53646263-Dodecen-1-ol, (3Z)-수율 91.6%

시약·촉매·용매 2

HCID 131709914Lindlars catalyst촉매HCID 8857Ethyl Acetate용매

실험 절차

To a solution of 3.20 g (17.5 mmoles) of 3-dodecyn-1-ol in 35 ml. of ethyl acetate was added 0.300 g of Lindlar catalyst (Lindlar, Helvetica Chimica Acta 35, 450 (1952)). The hydrogenation was carried out at atmospheric pressure with stirring. When the theoretical quantity of hydrogen had been taken up, the hydrogenation was stopped and the reaction mixture was filtered through Celite. After removal of the solvent, in vacuo, the residue was evaporatively distilled under reduced pressure to afford 2.95 g (91.6%) of (Z)-3-dodecen-1-ol as an oil.

후처리

  1. filtrationthe reaction mixture was filtered through Celite
  2. customAfter removal of the solvent
  3. distillationin vacuo, the residue was evaporatively distilled under reduced pressure

출처 및 근거

ORD 기록
ord-de7720d0f0d840a1bc1fb8d8b5d540fd
출처 데이터셋
uspto-grants-1984_02
특허 번호
US04434101

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