Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → Tetrahydro-N-methyl-N-(phosphonomethyl)-3-thiophenamine 1,1-dioxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | Phosphorous acid | HCID 107909 | — |
| 반응물 | 3-(Methylamino)-1lambda6-thiolane-1,1-dione hydrochloride | HCID 2770817 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Tetrahydro-N-methyl-N-(phosphonomethyl)-3-thiophenamine 1,1-dioxide | HCID 20509047 | 86.3% |
반응 단계
A mixture of N-methyltetrahydro-3-thiophenamine 1,1-dioxide hydrochloride (37.2 parts, 0.20 mole); 90 percent paraformaldehyde (6.8 parts, 0.22 mole); orthophosphorous acid (18.0 parts, 0.22 mole); and water (30 parts) was heated at its reflux temperature for 3 hours. After cooling, the solution was stirred into ethanol (150 ml.) and the sticky, white precipitate was triturated under more ethanol. After being dried in vacuo over P2O5 the product weighed 42.0 g. (86.3 percent yield). m.p. 222°-225° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04243524 |
| 출처 데이터셋 | uspto-grants-1981_01 |
| ORD ID | ord-6d49478bb54e4cd3bd5876e289607326 |
| 출처 메모 | uspto-grants-1981_01 |