Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bifonazole → HCID 178521215, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bifonazole | HCID 2378 | — |
| 반응물 | Phenacyl bromide | HCID 6259 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | HCID 178521215 | HCID 178521215 | 82.5% |
반응 단계
15.1 g (0.05 mol) of 1-[α-(4-biphenylyl)-benzyl]-imidazole and 10 g (0.05 mol) of ω-bromoacetophenone are suspended in 500 ml of acetonitrile. After stirring for 15 hours at room temperature, the resulting clear solution is concentrated to about 50 ml. The crystals which hereupon separate out are filtered off and dried. 21 g (82.5% of theory) of 1-[α-(4-biphenylyl)-benzyl]-3-phenacylimidazolium bromide of melting point 210° C. (with decomposition) are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04243670 |
| 출처 데이터셋 | uspto-grants-1981_01 |
| ORD ID | ord-49fe7d9561af495989e10a8de316869c |
| 출처 메모 | uspto-grants-1981_01 |