2-Naphthyl 4-piperidyl ketone hydrochloride → 4-[4-((4-Chloro-1-naphthyl)methyl)-1-piperidyl]-1-phenyl-1-butanone hydrochloride
반응식
Cl.[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([CH2:13][CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:5][CH:4]=1.Cl.N1CC[CH:24]([C:27]([C:29]2[CH:38]=[CH:37][C:36]3[C:31](=CC=CC=3)[CH:30]=2)=[O:28])[CH2:23][CH2:22]1>>[ClH:2].[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([CH2:13][CH:14]2[CH2:15][CH2:16][N:17]([CH2:22][CH2:23][CH2:24][C:27]([C:29]3[CH:38]=[CH:37][CH:36]=[CH:31][CH:30]=3)=[O:28])[CH2:18][CH2:19]2)=[CH:5][CH:4]=1참가 물질
3
실험 절차
When in the procedure of Example 19, 4-[(4-chloro-1-naphthyl)methyl]piperidine hydrochloride is substituted for 2-naphthyl 4-piperidyl ketone hydrochloride, 4-[4-((4-chloro-1-naphthyl)methyl)-1-piperidyl]-1-phenyl-1-butanone hydrochloride is produced.
출처 및 근거
- ORD 기록
- ord-e43d86adaf2540ecaa6b134b5f30d63b
- 출처 데이터셋
- uspto-grants-1981_01