Ethanol → HCID 23335847, 화합물

HRID 1390223노트

반응식

HRID 1390223 반응식
Cl[S:2]([CH:5]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH2:15][CH2:14][C:13]=2[CH:17]=1)[C:6]([OH:8])=[O:7])(=[O:4])=[O:3].[CH2:18]([OH:20])[CH3:19].C(N(CC)CC)C.O>C(OCC)(=O)C>[CH2:18]([O:20][S:2]([CH:5]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH2:15][CH2:14][C:13]=2[CH:17]=1)[C:6]([OH:8])=[O:7])(=[O:3])=[O:4])[CH3:19]

참가 물질

6

반응물 4

HCID 702EthanolHCID 962WaterHCID 8471TriethylamineHCID 23335839alpha-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid

생성물 1

HCID 23335847HCID 23335847, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매2회

실험 절차

α-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid (5 mmole) is added to 30 ml of ethyl acetate. To this mixture is added 5 mmole of ethanol in 10 ml of ethyl acetate which contains 10 mmole of triethylamine. The mixture is stirred at room temperature for about 1 hour and 50 ml of water is added. The pH is adjusted to about 6.5 and the layers separated. The organic layer is dried over magnesium sulfate, filtered and evaporated to give ethoxysulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid.

후처리

  1. customthe layers separated
  2. dry with materialThe organic layer is dried over magnesium sulfate
  3. filtrationfiltered
  4. customevaporated

출처 및 근거

ORD 기록
ord-d772c42358164a16995fa82176d9fb7a
출처 데이터셋
uspto-grants-1979_02
특허 번호
US04138397

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