참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Aminosalicylic Acid | HCID 4649 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Acetamidosalicylic acid | HCID 65509 | 92% |
반응 단계
30.6 grs (0.2 mol) p-aminosalicylic acid and 100 cc ethanol were introduced into a 250 ml flask, and the mixture was heated to 40° C. 20.4 grs (0.2 mol) acetic anhydride was then added at such a rate that the temperature did not exceed 50° C. When the addition was complete, the mixture was stirred at 50° C. for 3 hours. The product was filtered. Weight: 36 grs m.p. = 235° C. Yield = 92%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04138492 |
|---|
| 출처 데이터셋 | uspto-grants-1979_02 |
|---|
| ORD ID | ord-2ee3b3f9ce1b4fca9b70562dc0279e06 |
|---|
| 출처 메모 | uspto-grants-1979_02 |
|---|
