Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 6-(2-Benzylamino-2,2-dimethylethoxy)-nicotinic acid amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 6-Chloronicotinamide | HCID 80456 | — |
| 반응물 | 2-(Benzylamino)-2-methylpropan-1-ol | HCID 962368 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 6-(2-Benzylamino-2,2-dimethylethoxy)-nicotinic acid amide | HCID 53961034 | — |
반응 단계
Reaction of 47 g of 2-benzylamino-2-methyl-1-propanol, 13.3 g of sodium hydride dispersion and 23.5 g of 6-chloronicotinic acid amide in 300 ml of dimethylformamide analogously to Example 1 a) gives 6-(2-benzylamino-2,2-dimethyl-ethoxy)-nicotinic acid amide of melting point 125°-126° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04139623 |
| 출처 데이터셋 | uspto-grants-1979_02 |
| ORD ID | ord-290c21cb1e7d42f29d79c68a94cdff42 |
| 출처 메모 | uspto-grants-1979_02 |