Potassium Carbonate → HCID 70605331, 화합물

HRID 1390789노트

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HRID 1390789 반응식
[C:1]([O:4][C@H:5]1[CH2:10][CH2:9][C@H:8]2[C@H:11]3[C@H:25]([CH2:26][CH2:27][C@:6]12[CH3:7])[C@:19]1([CH2:20][O:21]C(=O)C)[C:14]([CH2:15][C@@H:16]([O:28][CH2:29][CH3:30])[CH2:17][CH2:18]1)=[CH:13][CH2:12]3)(=[O:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CO>[C:1]([O:4][C@H:5]1[CH2:10][CH2:9][C@H:8]2[C@H:11]3[C@H:25]([CH2:26][CH2:27][C@:6]12[CH3:7])[C@:19]1([CH2:20][OH:21])[C:14]([CH2:15][C@@H:16]([O:28][CH2:29][CH3:30])[CH2:17][CH2:18]1)=[CH:13][CH2:12]3)(=[O:3])[CH3:2]

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 86736330HCID 86736330, 화합물

생성물 1

HCID 70605331HCID 70605331, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

3β-Ethoxy-5-androstene-17β,19-diol diacetate is added to an aqueous methanol solution of potassium carbonate and the reaction solution stirred at room temperature for about 2 hours. The reaction mixture is poured onto water, and the oil which results is extracted into ether. The ether extract is washed with water, dried over magnesium sulfate and concentrated to dryness. Crystallization of the residue from an ether-pentane mixture yields 3β-ethoxy-5-androstene-17β,19-diol 17-acetate.

후처리

  1. additionThe reaction mixture is poured onto water
  2. customthe oil which results
  3. extractionis extracted into ether
  4. extractionThe ether extract
  5. washis washed with water
  6. dry with materialdried over magnesium sulfate
  7. concentrationconcentrated to dryness
  8. customCrystallization of the residue from an ether-pentane mixture

출처 및 근거

ORD 기록
ord-f74078a0cc58495790ea1fccafc1a9b3
출처 데이터셋
uspto-grants-1979_02
특허 번호
US04139617

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