1-(p-Tolyl)-4-(p-nitrobenzyl)piperazine → 1-(p-Tolyl)-4-[(4-aminophenyl)methyl]piperazine

HRID 1390978노트

반응식

HRID 1390978 반응식
[C:1]1([CH3:23])[CH:6]=[CH:5][C:4]([N:7]2[CH2:12][CH2:11][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=3)[CH2:9][CH2:8]2)=[CH:3][CH:2]=1>[Cl-].[Cl-].[Cl-].[Ti+3]>[C:1]1([CH3:23])[CH:2]=[CH:3][C:4]([N:7]2[CH2:8][CH2:9][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=3)[CH2:11][CH2:12]2)=[CH:5][CH:6]=1

참가 물질

3

반응물 1

HCID 213318671-(p-Tolyl)-4-(p-nitrobenzyl)piperazine

생성물 1

HCID 213318441-(p-Tolyl)-4-[(4-aminophenyl)methyl]piperazine

시약·촉매·용매 1

HCID 10313229titanium(III) trichloride촉매

실험 절차

In the manner given in Example 1B, 1-(p-tolyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(p-tolyl)-4-[(4-aminophenyl)methyl]piperazine.

출처 및 근거

ORD 기록
ord-12c744327bfa4ef58e90a3eb4147532f
출처 데이터셋
uspto-grants-1979_02
특허 번호
US04140775

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