Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanethiol → 3-(4-Methoxybenzylmercapto)-2-(methylthio)propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanethiol | HCID 878 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Bromo-3-(4-methoxybenzylmercapto)propanoic acid | HCID 20385290 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(4-Methoxybenzylmercapto)-2-(methylthio)propanoic acid | HCID 54057018 | — |
반응 단계
A solution of 2-bromo-3-(4-methoxybenzylmercapto)propanoic acid (15 g.), methylmercaptan (3 g.) and sodium hydroxide (4.6 g.) in 95% ethanol (25 ml.) is refluxed for twelve hours. The sodium bromide is filtered off and the filtrate is concentrated to dryness in vacuo. The residue is dissolved in water, acidified with concentrated hydrochloric acid and extracted with ethyl acetate. The organic layer is dried and concentrated to dryness to yield 3-(4-methoxybenzylmercapto)-2-(methythio)propanoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04140864 |
| 출처 데이터셋 | uspto-grants-1979_02 |
| ORD ID | ord-ba37de8ceaa246fa9770dd2df872a9d3 |
| 출처 메모 | uspto-grants-1979_02 |