Thionyl Chloride → 5-Chloro-1-benzofuran-2-carbonyl chloride

HRID 1391831

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10](O)=[O:11])=[CH:7][C:6]=2[CH:13]=1.S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]([Cl:16])=[O:11])=[CH:7][C:6]=2[CH:13]=1

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 9378385-Chloro-1-benzofuran-2-carboxylic acid

생성물 1

HCID 337407645-Chloro-1-benzofuran-2-carbonyl chloride

실험 절차

A solution of 5-chloro-1-benzofuran-2-carboxylic acid (827 mg, 42 mmol) in thionyl chloride (4 mL) was refluxed over night. The solvent was removed in vacuo to give the 5-chloro-1-benzofuran-2-carbonyl chloride in quantitative yield.

후처리

customThe solvent was removed in vacuo

출처 및 근거

ORD 기록: ord-1371deb182bc4d92a6767f85cf58b3b7
출처 데이터셋: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07339059B2

연결된 노트

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