Water → Quinoline
반응식
C([C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1)=O.CC1C([P+](OC(C)=O)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=CC=1.O>C1(C)C=CC=CC=1>[N:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:11]=[CH:12][CH:3]=1참가 물질
5
실험 절차
0.2 g (1.27 mmol) of 2-formylquinoline is dissolved in 10 ml of anhydrous toluene, in a dry round-bottomed flask equipped with a magnetic stirrer and a nitrogen inlet. 0.51 g (1.52 mmol) of methyl(triphenylphosphoranylidene) acetate is added. The reaction mixture is brought to the reflux temperature of toluene for 90 minutes, and the solution is then slowly returned to ambient temperature and hydrolyzed with 10 ml of water.
후처리
- customequipped with a magnetic stirrer and a nitrogen inlet
출처 및 근거
- ORD 기록
- ord-c61bee9ad7c34fa3ac98e6a0b700925a
- 출처 데이터셋
- uspto-grants-2008_03
- 특허 번호
- US07342026B2
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