Methyl but-2-enoate → 3-(4-Nitro-imidazol-1-yl)-butyric acid methyl ester

HRID 1392438노트

반응식

HRID 1392438 반응식
[N+:1]([C:4]1[N:5]=[CH:6][NH:7][CH:8]=1)([O-:3])=[O:2].[CH3:9][O:10][C:11](=[O:15])[CH:12]=[CH:13][CH3:14]>>[CH3:9][O:10][C:11](=[O:15])[CH2:12][CH:13]([N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[N:5]=[CH:6]1)[CH3:14]

참가 물질

3

반응물 2

HCID 12181Methyl but-2-enoateHCID 178526856HCID 178526856, 화합물

생성물 1

HCID 435364023-(4-Nitro-imidazol-1-yl)-butyric acid methyl ester

실험 절차

4-nitroimidazole was reacted with methyl-3-methylacrylate to provide the title compound: 1H NMR (400 MHz, CDCl3) 1.62 (d, 3H, J=7.0 Hz), 2.81 (d, 2H, J=7.0 Hz), 3.66 (s, 3H), 4.78 (m, 1H), 7.53 (d, 1H, J=1.6 Hz), 7.82 (d, 1H, J=1.6 Hz); MS m/z 214.1(M+1).

출처 및 근거

ORD 기록
ord-a65179dc4de04151acb0e78c2d17845f
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07342118B2

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