5,7-Dimethyl-2-tetralone → HCID 11590818, 화합물

HRID 1392505노트

반응식

HRID 1392505 반응식
[CH3:1][C:2]([N:10]1[CH:14]=[C:13]([NH:15][C:16](=[O:22])[CH:17]([NH2:21])[CH2:18][CH2:19][CH3:20])[N:12]=[CH:11]1)([CH3:9])[CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1.[CH3:23][C:24]1[CH:33]=[C:32]([CH3:34])[CH:31]=[C:30]2[C:25]=1[CH2:26][CH2:27][C:28](=O)[CH2:29]2>>[CH3:1][C:2]([N:10]1[CH:14]=[C:13]([NH:15][C:16](=[O:22])[CH:17]([NH:21][CH:28]2[CH2:27][CH2:26][C:25]3[C:30](=[CH:31][C:32]([CH3:34])=[CH:33][C:24]=3[CH3:23])[CH2:29]2)[CH2:18][CH2:19][CH3:20])[N:12]=[CH:11]1)([CH3:9])[CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1

참가 물질

3

반응물 2

HCID 103972765,7-Dimethyl-2-tetraloneHCID 671642262-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide

생성물 1

HCID 11590818HCID 11590818, 화합물

실험 절차

2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide was reacted with 5,7-dimethyl-3,4-dihydro-1H-naphthalen-2-one to provide the title compound: C13 NMR (100 MHz, CDCl3) 14.2, 19.5, 19.6, 21.0, 24.3, 25.3, 25.6, 26.6, 29.7, 30.7, 36.6, 37.1, 38.0, 53.0, 53.3, 56.0, 59.1, 60.4, 60.8, 67.3, 104.7, 127.9, 28.0, 128.6, 128.7, 131.1, 131.3, 131.6, 134.6, 135.1, 135.2, 136.4, 137.3, 172.5, 172.6; MS m/z 466.5 (M+1).

출처 및 근거

ORD 기록
ord-424b11dfce3c4aeaa5a5ec9a4f54a4d9
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07342118B2

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