Aluminium lithium hydride → HCID 23033941, 화합물

HRID 1393351노트

반응식

HRID 1393351 반응식
[N:1]1([C:7]2[S:8][C:9]3[C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=[CH:12][C:10]=3[N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[N:1]1([C:7]2[S:8][C:9]3[C:15]([CH2:16][OH:17])=[CH:14][CH:13]=[CH:12][C:10]=3[N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 21226445Aluminium lithium hydrideHCID 23033856HCID 23033856, 화합물

생성물 1

HCID 23033941HCID 23033941, 화합물수율 92.1%

실험 절차

Ethyl ester of 2-piperidinobenzothiazole-7-carboxylic acid (475 mg, 1.64 mmol) was reduced by using lithium aluminium hydride as in Preparation 2-3) to give 2-piperidinobenzothiazole-7-methanol (375 mg, 91%) as pale yellow crystals.

후처리

  1. customas in Preparation 2-3)

출처 및 근거

ORD 기록
ord-b845774a6baf4daba8c37c342ae9dc46
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07345068B2

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