1-Bromooctane → N,N,N-Triethyloctan-1-aminium bromide

HRID 1395975노트

반응식

HRID 1395975 반응식
[CH2:1]([N:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2].[Br:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>C(#N)C>[Br-:8].[CH2:1]([N+:3]([CH2:6][CH3:7])([CH2:4][CH3:5])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:2]

참가 물질

4

반응물 2

HCID 81401-BromooctaneHCID 8471Triethylamine

생성물 1

HCID 21951230N,N,N-Triethyloctan-1-aminium bromide수율 72.4%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

반응 조건

온도
80 °C

실험 절차

A 100 ml flask was purged with nitrogen before 8.84 g (0.087 mol) of triethylamine, 20.33 g (0.105 mol) of 1-bromoctane and 31.04 g of acetonitrile were introduced into the flask. The mixture was stirred under protective nitrogen gas at 80° C. for 48 hours. Volatiles were then drawn off under reduced pressure. The crude product was crystallized from an ethyl acetate/acetone mixture to obtain 18.55 g (0.063 mol) of triethyloctylammonium bromide (white hygroscopic crystals). The yield was 72%, based on triethylamine.

후처리

  1. additionwere introduced into the flask
  2. customThe crude product was crystallized from an ethyl acetate/acetone mixture

출처 및 근거

ORD 기록
ord-4be0e1afb728492384c46609f9bf4d3a
출처 데이터셋
uspto-grants-2014_12
특허 번호
US08901054B2

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