Sulfuric Acid → HCID 86630407, 화합물
반응식
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11]1[C:19]2[C:14](=[N:15][C:16]([NH2:20])=[N:17][CH:18]=2)[N:13]([CH3:21])[N:12]=1.[S:22](=O)(=[O:25])([OH:24])[OH:23]>>[NH2:20][C:16]1[N:15]=[C:14]2[N:13]([CH3:21])[N:12]=[C:11]([C:4]3[C:3]([O:2][CH3:1])=[CH:8][C:7]([O:9][CH3:10])=[C:6]([S:22]([OH:25])(=[O:24])=[O:23])[CH:5]=3)[C:19]2=[CH:18][N:17]=1참가 물질
3
실험 절차
3-(2,4-Dimethoxy-phenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamine (Example 89) (1 g, 3.50 mmol) is dissolved in concentrated sulfuric acid (25 ml) to give a blood red solution. The reaction mixture is stirred at room temperature overnight, poured onto ice-water (200 ml) and the resulting solid is collected by filtration, washed with water and dried under vacuum to afford the title compound.
후처리
- customto give a blood red solution
- additionpoured onto ice-water (200 ml)
- filtrationthe resulting solid is collected by filtration
- washwashed with water
- customdried under vacuum