Trichloroisocyanuric Acid → HCID 68967195, 화합물
반응식
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11]1[C:19]2[C:14](=[N:15][C:16]([NH2:20])=[N:17][CH:18]=2)[N:13]([CH3:21])[N:12]=1.[Cl:22]N1C(=O)N(Cl)C(=O)N(Cl)C1=O>C(#N)C>[Cl:22][C:6]1[C:7]([O:9][CH3:10])=[CH:8][C:3]([O:2][CH3:1])=[C:4]([C:11]2[C:19]3[C:14](=[N:15][C:16]([NH2:20])=[N:17][CH:18]=3)[N:13]([CH3:21])[N:12]=2)[CH:5]=1참가 물질
4
실험 절차
3-(2,4-Dimethoxy-phenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamine (Example 89) is suspended in acetonitrile (10 ml), trichloroisocyanuric acid (0.021 g, 0.09 mmol) is added and the reaction mixture is stirred for 1.5 hours at room temperature then stood overnight. The solvents are removed in vacuo, the residue is dissolved in EtOAc, washed with water and brine, dried over MgSO4, filtered, concentrated in vacuo and dried under vacuum (45° C.) to afford the title compound.