2-Chloro-5-(chloromethyl)thiophene → N-Benzyl-2-(4-((5-chlorothiophen-2-yl)methoxy)-2-oxopyridin-1(2H)-yl)-4-methylthiazole-5-carboxamide

반응식

[CH2:9]([c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)[NH:16][C:17](=[O:18])[c:19]1[c:20]([CH3:32])[n:21][c:22](-[n:24]2[c:25](=[O:31])[cH:26][c:27]([OH:30])[cH:28][cH:29]2)[s:23]1.[Cl:1][c:2]1[s:3][c:4]([CH2:7][Cl:8])[cH:5][cH:6]1>>[Cl:1][c:2]1[s:3][c:4]([CH2:7][O:30][c:27]2[cH:26][c:25](=[O:31])[n:24](-[c:22]3[n:21][c:20]([CH3:32])[c:19]([C:17]([NH:16][CH2:9][c:10]4[cH:11][cH:12][cH:13][cH:14][cH:15]4)=[O:18])[s:23]3)[cH:29][cH:28]2)[cH:5][cH:6]1

참가 물질

반응물 2

HCID 5830792-Chloro-5-(chloromethyl)thiophene

HCID 54742338N-benzyl-2-(4-hydroxy-2-oxopyridin-1(2H)-yl)-4-methylthiazole-5-carboxamide

생성물 1

HCID 57744508N-Benzyl-2-(4-((5-chlorothiophen-2-yl)methoxy)-2-oxopyridin-1(2H)-yl)-4-methylthiazole-5-carboxamide

출처 및 근거

ORD 기록: ord-5fe17da1911d43b285fcd9d9401bb6f8
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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