Boronic Acid → [2,2′-Bifuran]-5-carboxaldehyde

반응식

B(O)O.Br[C:5]1[O:9][C:8]([CH:10]=[O:11])=[CH:7][CH:6]=1.[O:12]1[CH:16]=[CH:15][CH:14]=[C:13]1B(O)O>>[O:9]1[C:8]([CH:10]=[O:11])=[CH:7][CH:6]=[C:5]1[C:13]1[O:12][CH:16]=[CH:15][CH:14]=1

참가 물질

반응물 3

HCID 61668Boronic Acid

HCID 6003285-Bromofuran-2-carbaldehyde

HCID 2734357Furan-2-boronic acid

생성물 1

HCID 11469241[2,2′-Bifuran]-5-carboxaldehyde

실험 절차

[2,2′-bifuran]-5-carbaldehyde was prepared using the general boronic acid coupling procedure with 5-bromofuran-2-carbaldehyde and furan-2-ylboronic acid (24 mg, 93 mg theoretical, 25.8%). LC-MS m/z 163 (M+1).

출처 및 근거

ORD 기록: ord-6099645d9818450ab9207ca47e096b20
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08901145B2

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