Boronic Acid → 4-(Furan-2-yl)thiophene-2-carbaldehyde

반응식

B(O)O.Br[C:5]1[CH:6]=[C:7]([CH:10]=[O:11])[S:8][CH:9]=1.[O:12]1[CH:16]=[CH:15][CH:14]=[C:13]1B(O)O>>[O:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:5]1[CH:6]=[C:7]([CH:10]=[O:11])[S:8][CH:9]=1

참가 물질

반응물 3

HCID 61668Boronic Acid

HCID 877924-Bromothiophene-2-carbaldehyde

HCID 2734357Furan-2-boronic acid

생성물 1

HCID 230048654-(Furan-2-yl)thiophene-2-carbaldehyde

실험 절차

4-(furan-2-yl)thiophene-2-carbaldehyde was prepared using the general boronic acid coupling procedure with 4-bromothiophene-2-carbaldehyde and furan-2-ylboronic acid (26 mg, 93 mg theoretical, 28.0%). LC-MS m/z 179 (M+1).

출처 및 근거

ORD 기록: ord-8f7cd8ddb80248a880c5ac1a9062d9d2
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08901145B2

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