Sodium Bicarbonate → HCID 178434210, 화합물
반응식
[Br:1][C:2]1[C:7]([F:8])=[CH:6][C:5](/[C:9](=[N:11]/[NH2:12])/[CH3:10])=[C:4](F)[CH:3]=1.C([O-])(O)=O.[Na+]>C(O)CO>[Br:1][C:2]1[CH:3]=[C:4]2[C:5]([C:9]([CH3:10])=[N:11][NH:12]2)=[CH:6][C:7]=1[F:8]참가 물질
4
실험 절차
A solution of (E)-[1-(4-bromo-2,5-difluorophenyl)ethylidene]hydrazine in ethylene glycol (3 mL) was heated at 165° C. for 3 hours in a sealed tube. The mixture was cooled to RT and saturated NaHCO3 was added (3 mL) and stirred for 10 minutes. The mixture was filtered and solid was washed with water (5 mL×2) to obtain the desired product brown solid (163 mg, 62%).
후처리
- filtrationThe mixture was filtered
- washsolid was washed with water (5 mL×2)
출처 및 근거
- ORD 기록
- ord-f98666d4f79246418018fbf0d9bcad77
- 출처 데이터셋
- uspto-grants-2014_12
- 특허 번호
- US08901313B2
반응 노트
불러오는 중…