HCID 86632878, 화합물 → HCID 68737602, 화합물
반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-])=O)[C:5]=1[NH:13][CH2:14][CH2:15][CH2:16][OH:17])([O-])=O>[Pd].O1CCCC1>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([NH2:10])[C:5]=1[NH:13][CH2:14][CH2:15][CH2:16][OH:17]참가 물질
4
실험 절차
Under hydrogen gas atmosphere, a mixture of 3-[(2,6-dinitrophenyl)amino]propan-1-ol (Reference Example 114; 17.7 g, 73.3 mmol), 10% palladium on carbon (50% wet, 3.5 g) and tetrahydrofuran (360 mL) was stirred at room temperature for 6 hr. The reaction mixture was filtered and concentrated in vacuo to give the title compound as an oil (12.1 g, 66.7 mmol, 91%).
후처리
- filtrationThe reaction mixture was filtered
- concentrationconcentrated in vacuo
출처 및 근거
- ORD 기록
- ord-66fa1d73ef42472496fac7f60287b43b
- 출처 데이터셋
- uspto-grants-2014_12
- 특허 번호
- US08901141B2
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