2-Bromo-5-ethylthiophene → 2-(4'-Ethyl-2,6-difluorobiphenyl-4-yl)-5-ethylthiophene

HRID 1399414노트

반응식

HRID 1399414 반응식
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([F:15])=[CH:13][C:12](B(O)O)=[CH:11][C:10]=2[F:19])=[CH:5][CH:4]=1)[CH3:2].Br[C:21]1[S:22][C:23]([CH2:26][CH3:27])=[CH:24][CH:25]=1>>[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([F:15])=[CH:13][C:12]([C:21]3[S:22][C:23]([CH2:26][CH3:27])=[CH:24][CH:25]=3)=[CH:11][C:10]=2[F:19])=[CH:5][CH:4]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 227291122-Bromo-5-ethylthiopheneHCID 666251904'-Ethyl-2,6-difluoro-4-biphenylboronic acid

생성물 1

HCID 580284542-(4'-Ethyl-2,6-difluorobiphenyl-4-yl)-5-ethylthiophene

실험 절차

The compound 2-(4′-ethyl-2,6-difluorobiphenyl-4-yl)-5-ethylthiophene (SUP-2-2) is prepared analogously to Example 1 from 4′-ethyl-2,6-difluoro-4-biphenylboronic acid and 2-bromo-5-ethylthiophene.

출처 및 근거

ORD 기록
ord-d721801986a84c6c98021cc7a854e9f3
출처 데이터셋
uspto-grants-2014_12
특허 번호
US08906261B2

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