5-Chloro-2-furaldehyde → 5-Chloro-6-(2-{[(5-chlorofuran-2-yl)methyl]amino}ethoxy)naphthalene-2-carbonitrile

반응식

[Cl-].[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([C:13]#[N:14])=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[O:15][CH2:16][CH2:17][NH3+:18].[Cl:19][C:20]1[O:24][C:23]([CH:25]=O)=[CH:22][CH:21]=1>>[Cl:2][C:3]1[C:4]([O:15][CH2:16][CH2:17][NH:18][CH2:25][C:23]2[O:24][C:20]([Cl:19])=[CH:21][CH:22]=2)=[CH:5][CH:6]=[C:7]2[C:12]=1[CH:11]=[CH:10][C:9]([C:13]#[N:14])=[CH:8]2

참가 물질

반응물 2

HCID 27696305-Chloro-2-furaldehyde

HCID 681512872-[(1-Chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride

생성물 1

HCID 590536635-Chloro-6-(2-{[(5-chlorofuran-2-yl)methyl]amino}ethoxy)naphthalene-2-carbonitrile수율 60%

실험 절차

Prepared from 2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride and 5-chlorofuran-2-carbaldehyde in 60% yield as a yellow oil.

출처 및 근거

ORD 기록: ord-8a742cc523234cebbd5c4b49b64365b8
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08906946B2

반응 노트

불러오는 중…